Description

4-Bromophenylacetone is a versatile brominated aromatic ketone intermediate of significant importance in advanced organic synthesis. Its value lies in providing a reactive phenylacetone scaffold with a bromine substituent, enabling selective functionalization for building complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as pharmaceutical intermediate synthesis and ligand preparation.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing substituted phenethylamine or arylalkylamine motifs.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in metal-catalyzed cross-coupling reactions.
• Organic Synthesis Research: Employed in academic and industrial R&D for constructing complex organic molecules via reactions like alkylation, condensation, or further halogen-metal exchange.
• Material Science Precursor: Can be utilized in the development of organic electronic materials and specialty polymers.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-Bromophenylacetone
CAS No.	6186-22-7
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	1-(4-Bromophenyl)-2-propanone; p-Bromophenylacetone; 4'-Bromophenylacetone; 4-Bromobenzyl methyl ketone; 1-(4-Bromophenyl)acetone; 4-Bromo-ω-methylacetophenone; USEPA/OPP Pesticide Code 128925; NSC 406908
EINECS	228-246-5

Quality Control

Our 4-Bromophenylacetone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, physical properties, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.