Description

1-(4-Hydroxy-3-Methoxyphenyl)-2-Nitroethene is a versatile nitroalkene derivative and a key synthetic intermediate in organic chemistry. This compound matters for its role as a crucial building block in the synthesis of complex molecules, particularly in pharmaceutical and fine chemical research. Industries that need it include pharmaceutical R&D for developing new active ingredients, agrochemical manufacturers for creating novel crop protection agents, and academic laboratories focused on organic synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various pharmacologically active compounds, including potential cardiovascular and central nervous system agents.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactive nitroethene functionality.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and other specialty chemicals requiring specific aromatic nitroalkene structures.
• Organic Synthesis Research: Employed in academic and industrial R&D for Michael addition reactions, cycloadditions, and the construction of complex heterocyclic systems.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing certain aroma chemicals derived from substituted phenylpropanoids.
• Material Science: Investigated as a monomer or cross-linking agent in the development of advanced polymeric materials.

Basic Information

Product Name	1-(4-Hydroxy-3-Methoxyphenyl)-2-Nitroethene
CAS No.	6178-42-3
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	2-Nitro-1-(4-hydroxy-3-methoxyphenyl)ethene; 4-Hydroxy-3-methoxy-β-nitrostyrene; 3-Methoxy-4-hydroxy-β-nitrostyrene; Vanillin nitroethylene; (E)-1-(4-Hydroxy-3-methoxyphenyl)-2-nitroethene; Nitrovinylguaiacol; Guaiacol nitroethylene derivative
EINECS	Contact for details

Quality Control

Our 1-(4-Hydroxy-3-Methoxyphenyl)-2-Nitroethene is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its potential sensitivity, store separately from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.