Description

cis-2,2'-(1-Methylpiperidine-2,6-Diyl)Bis[1-Phenylethan-1-One] Hydrochloride is a high-purity, synthetic organic compound supplied as a hydrochloride salt to enhance stability and handling. This compound serves as a critical chiral intermediate or building block in advanced pharmaceutical synthesis, particularly for the development of active pharmaceutical ingredients (APIs) with complex stereochemistry. It is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel therapeutic agents, including potential central nervous system (CNS) drugs and receptor modulators.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Academic & R&D Laboratories: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and novel compound library synthesis.
• Fine Chemical Synthesis: An intermediate in the multi-step production of specialty chemicals requiring precise molecular architecture.

Basic Information

Product Name	cis-2,2'-(1-Methylpiperidine-2,6-Diyl)Bis[1-Phenylethan-1-One] Hydrochloride
CAS No.	6168-88-3
Molecular Formula	C23H28ClNO2
Molecular Weight	385.93 g/mol
Synonyms	1,1'-(2,6-cis-1-Methyl-2,6-piperidinediyl)bis[1-phenylethanone] hydrochloride; cis-1-Methyl-2,6-bis(phenacyl)piperidine hydrochloride; 2,2'-(1-Methylpiperidine-2,6-diyl)di-1-phenylethanone hydrochloride (cis isomer); (2R,6S)-1-Methyl-2,6-bis(2-oxo-2-phenylethyl)piperidinium chloride; (2S,6R)-1-Methyl-2,6-bis(2-oxo-2-phenylethyl)piperidinium chloride; cis-1-Methyl-2,6-diphenacylpiperidine hydrochloride; CAS 6168-88-3
EINECS	Contact for details

Quality Control

Our cis-2,2'-(1-Methylpiperidine-2,6-Diyl)Bis[1-Phenylethan-1-One] Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) confirming identity, purity, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% cis isomer
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.