Description

2-Thiopheneboronic Acid is a versatile organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its primary value lies in enabling the efficient and selective formation of carbon-carbon bonds, facilitating the construction of complex molecular architectures. This compound is critically needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing active ingredients, functional polymers, and advanced electronic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for synthesizing biaryl and heteroaryl compounds, which are core structures in many pharmaceuticals and organic electronic materials.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs), especially those containing thiophene or complex aryl motifs.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that require specific thiophene-based active components.
• Material Science & OLED Development: Serves as a precursor for synthesizing organic semiconductors, light-emitting diodes (OLEDs), and conductive polymers.
• Ligand Synthesis for Catalysis: Used to prepare specialized ligands for transition metal catalysts used in asymmetric synthesis and other advanced catalytic processes.
• Chemical Research & Library Synthesis: A fundamental tool in medicinal chemistry for creating diverse compound libraries for high-throughput screening and drug discovery.

Basic Information

Item	Details
Product Name	2-Thiopheneboronic Acid
CAS No.	6165-68-0
Molecular Formula	C4H5BO2S
Molecular Weight	127.96 g/mol
Synonyms	2-Thienylboronic Acid; Thiophene-2-boronic Acid; 2-Thiophenylboronic Acid; (Thiophen-2-yl)boronic Acid; 2-Boronothiophene; 2-Thienyl-B(OH)2; 2-Thiophene Boronic Acid; B-(2-Thienyl)boronic Acid
EINECS	228-218-8

Quality Control

Our 2-Thiopheneboronic Acid is produced under stringent quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and moisture content. Our quality systems are designed to meet the rigorous standards required for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.