Description

3'-tert-Butylacetophenone (CAS NO 6136-71-6) is a versatile aromatic ketone derivative valued for its role as a key synthetic intermediate in advanced organic synthesis. Its molecular structure, featuring both a tert-butyl group and an acetyl moiety, makes it a crucial building block for constructing more complex molecules with specific steric and electronic properties. This compound is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a sterically hindered aromatic ketone framework.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the tert-butylacetophenone core provides specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fragrance and Flavor Chemistry: Acts as an intermediate for creating musk-like aromatic compounds and other specialty odorants.
• Polymer and Material Science: Employed in the synthesis of monomers and photoinitiators for advanced polymers and UV-curable resins.
• Organic Synthesis Building Block: Utilized in Friedel-Crafts acylation reactions and other transformations to introduce the 3'-tert-butylacetophenone moiety into target molecules.

Basic Information

Product Name	3'-tert-Butylacetophenone
CAS No.	6136-71-6
Molecular Formula	C12H16O
Molecular Weight	176.26 g/mol
Synonyms	1-(3-tert-Butylphenyl)ethanone; 3'-tert-Butyl Acetophenone; 1-Acetyl-3-tert-butylbenzene; m-tert-Butylacetophenone; 3-(1-Oxoethyl)-tert-butylbenzene; 3-tert-Butylphenyl methyl ketone; Ethanone, 1-[3-(1,1-dimethylethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 3'-tert-Butylacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.