Description

trans-Methyl 4-Hydroxycyclohexanecarboxylate is a high-purity chiral intermediate and versatile building block in advanced organic synthesis. Its value lies in the functionalized cyclohexane ring and ester group, which are critical for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, especially those targeting the central nervous system (CNS) and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides where the stereochemistry of the cyclohexane ring influences biological activity.
• Liquid Crystal Materials: Serves as a precursor for cyclohexane-based derivatives used in liquid crystal displays (LCDs) and optical materials.
• Fragrance and Flavor Chemistry: Intermediate for creating synthetic musks and other complex aroma chemicals with specific olfactory profiles.
• Polymer Modification: Acts as a monomer or cross-linking agent for specialty polymers, enhancing thermal stability and mechanical properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral pool starting material in stereoselective catalytic reactions.

Basic Information

Product Name	trans-Methyl 4-Hydroxycyclohexanecarboxylate
CAS No.	6125-57-1
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	trans-4-Hydroxycyclohexanecarboxylic Acid Methyl Ester; Methyl trans-4-Hydroxycyclohexanecarboxylate; (1r,4r)-4-Hydroxycyclohexanecarboxylic Acid Methyl Ester; Methyl (1r,4r)-4-Hydroxycyclohexanecarboxylate; Methyl 4-Hydroxycyclohexanecarboxylate (trans-); trans-Methyl 4-Hydroxycyclohexanecarboxylate; 4-Hydroxycyclohexanecarboxylic Acid Methyl Ester, trans-; M4HCC
EINECS	Contact for details

Quality Control

Our trans-Methyl 4-Hydroxycyclohexanecarboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage under an inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (trans-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.