Description

Dl-Methyl-4,4,4,4,4,4-Hexafluorovalinate,Hcisalt CAS NO 6063-80-2 is a high-purity fluorinated amino acid derivative, specifically the hydrochloride salt of the methyl ester. This compound is valued for its role as a critical advanced synthetic intermediate in the development of complex molecules, particularly due to the unique properties imparted by the hexafluoroisopropyl moiety. It is primarily sought after by pharmaceutical research and agrochemical development teams for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated peptides, protease inhibitors, and other bioactive molecules where enhanced metabolic stability and lipophilicity are desired.
• Agrochemical Research: Used in the development of next-generation herbicides and pesticides, leveraging fluorine's ability to improve compound efficacy and environmental persistence.
• Material Science: Serves as a precursor for specialty polymers and coatings that require specific surface properties, chemical resistance, or low surface energy.
• Chemical Biology & Proteomics: Employed as a tagged amino acid analog in studies of protein structure, function, and interaction, utilizing fluorine as an NMR-active probe.
• Organic Synthesis: A versatile reagent for introducing the hexafluoroisopropyl group into complex molecular architectures, enabling fine-tuning of physical and chemical properties.

Basic Information

Product Name	Dl-Methyl-4,4,4,4,4,4-Hexafluorovalinate,Hcisalt
CAS No.	6063-80-2
Molecular Formula	C7H9F6NO2 • HCl
Molecular Weight	289.60 g/mol (Free base: 253.14 g/mol)
Synonyms	DL-4,4,4,4,4,4-Hexafluorovaline Methyl Ester Hydrochloride; Methyl 2-Amino-3-(1,1,1,3,3,3-hexafluoro-2-propyl)propanoate Hydrochloride; (RS)-Methyl 2-amino-3-(1,1,1,3,3,3-hexafluoropropan-2-yl)propanoate hydrochloride; Hexafluorovaline Methyl Ester HCl; Methyl 4,4,4,4,4,4-hexafluorovalinate hydrochloride; F6Val-OMe • HCl; 2-Amino-3-(1,1,1,3,3,3-hexafluoro-2-propyl)propionic Acid Methyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our Dl-Methyl-4,4,4,4,4,4-Hexafluorovalinate,Hcisalt is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (typically ~50:50)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.