Description

Cyclohexaneacetonitrile, 1-Fluoro-α-Hydroxy- is a specialized fluorinated nitrile building block with significant synthetic utility. This compound is valued for its unique molecular structure, which combines a cyclohexyl backbone with a reactive nitrile group and a fluorinated α-hydroxy moiety, enabling precise modifications in complex organic syntheses. It is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of fluorinated drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine atom can enhance biological activity and environmental stability.
• Advanced Material Precursor: Serves as a monomer or functionalizing agent in the development of specialty polymers and liquid crystals with tailored properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures via reactions at the nitrile or hydroxyl functional groups.
• Fluorine Chemistry Research: An important substrate for studying fluorination reactions and the stereochemical influence of fluorine in organic molecules.

Basic Information

Product Name	Cyclohexaneacetonitrile, 1-Fluoro-α-Hydroxy-
CAS No.	699-43-4
Molecular Formula	C8H12FNO
Molecular Weight	157.19 g/mol
Synonyms	1-Fluoro-1-hydroxycyclohexaneacetonitrile; α-Fluoro-α-hydroxycyclohexylacetonitrile; 2-(1-Fluoro-1-hydroxycyclohexyl)acetonitrile; (1-Fluoro-1-hydroxycyclohexyl)acetonitrile; Cyclohexyl(fluoro)(hydroxy)acetonitrile; 699-43-4; Fluorohydroxycyclohexylacetonitrile
EINECS	Contact for details

Quality Control

Our production of Cyclohexaneacetonitrile, 1-Fluoro-α-Hydroxy- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques, including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of reactive functional groups, it is recommended to store under an inert atmosphere for long-term stability and to minimize potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.