Description

1-Methoxy-2,3-Dihydro-1H-Phosphole 1-Oxide is a specialized organophosphorus compound that serves as a valuable building block and intermediate in advanced chemical synthesis. Its unique heterocyclic structure, featuring a phosphole oxide core, makes it a critical reagent for developing novel materials and active pharmaceutical ingredients (APIs). This chemical is primarily sought by research and development teams, as well as production chemists, in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic pathways.
• Ligand Precursor in Catalysis: Used to develop chiral phosphine ligands for asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Agrochemical Research: Intermediate in the creation of new-generation herbicides, pesticides, and plant growth regulators with improved efficacy.
• Material Science: Serves as a monomer or additive in the development of specialty polymers, flame retardants, and electronic materials.
• Organic Synthesis Reagent: Employed in cyclization reactions, phosphorylation, and as a scaffold for constructing complex heterocycles in academic and industrial R&D.
• Coordination Chemistry: Acts as a precursor for metal-organic frameworks (MOFs) and complexes used in sensing and catalysis applications.

Basic Information

Product Name	1-Methoxy-2,3-Dihydro-1H-Phosphole 1-Oxide
CAS No.	694-66-6
Molecular Formula	C5H9O2P
Molecular Weight	132.10 g/mol
Synonyms	1-Methoxy-2,3-dihydro-1H-phosphole 1-oxide; 1-Methoxy-2,5-dihydro-1H-phosphole 1-oxide; 1-Methoxy-2,3-dihydrophosphole 1-oxide; 2,3-Dihydro-1-methoxy-1H-phosphole 1-oxide; Phosphole oxide, 1-methoxy-2,3-dihydro-; 1H-Phosphole, 2,3-dihydro-1-methoxy-, 1-oxide
EINECS	Contact for details

Quality Control

Our 1-Methoxy-2,3-Dihydro-1H-Phosphole 1-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.