Description

(1E,3Z)-1,3-Butadiene-1,4-Dicarboxylic Acid Dimethyl Ester is a high-purity, conjugated diene diester that serves as a versatile and critical building block in advanced organic synthesis. Its unique (1E,3Z) stereochemistry and reactive diene system make it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty polymer sectors for applications such as Diels-Alder cycloadditions and fine chemical production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex bioactive molecules and active pharmaceutical ingredients (APIs) via cycloaddition and functionalization reactions.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging its reactivity to form heterocyclic cores.
• Specialty Polymer & Material Science: Acts as a monomer or cross-linking agent for creating polymers with specific optical, electronic, or mechanical properties.
• Diels-Alder Reactions: Serves as a classic, highly reactive diene component in [4+2] cycloadditions to construct six-membered carbocycles and heterocycles.
• Fine Chemical & Fragrance Manufacturing: Utilized in the multi-step synthesis of complex fragrance compounds and other high-value fine chemicals.
• Academic & Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and catalysis research.

Basic Information

Item	Details
Product Name	(1E,3Z)-1,3-Butadiene-1,4-Dicarboxylic Acid Dimethyl Ester
CAS No.	692-92-2
Molecular Formula	C8H10O4
Molecular Weight	170.16 g/mol
Synonyms	Dimethyl (1E,3Z)-1,3-Butadiene-1,4-dicarboxylate; (1E,3Z)-2,4-Hexadienedioic Acid Dimethyl Ester; Dimethyl (E,Z)-Muconate; (E,Z)-Dimethyl Muconate; trans,cis-Dimethyl Muconate; (1E,3Z)-Dimethyl Muconate; Muconic Acid Dimethyl Ester (E,Z-isomer); 2,4-Hexadienedioic Acid, Dimethyl Ester, (1E,3Z)-
EINECS	211-746-8

Quality Control

Our (1E,3Z)-1,3-Butadiene-1,4-Dicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure high chemical purity, precise stereochemical integrity, and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (GC/HPLC)	≥ 95.0% (1E,3Z)-isomer
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.