Description

Trifluoroethenesulfonyl Fluoride is a highly reactive and versatile fluorinated sulfonyl fluoride building block. This compound is critical for introducing the trifluoroethenesulfonyl (TfE) group, a powerful electron-withdrawing moiety, into target molecules. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drugs and bioactive molecules, leveraging its strong electron-withdrawing properties.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the TfE group enhances metabolic stability and activity.
• Polymer & Material Science: Serves as a monomer or modifier for producing specialty polymers with unique surface properties, chemical resistance, and thermal stability.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorination Reagent: Acts as a source of the trifluoroethenesulfonyl group in nucleophilic substitution and coupling reactions.
• Chemical Research & Development: A valuable tool for medicinal chemistry and process R&D for exploring new chemical spaces and reaction pathways.

Basic Information

Product Name	Trifluoroethenesulfonyl Fluoride
CAS No.	684-10-6
Molecular Formula	C2F4O2S
Molecular Weight	164.08 g/mol
Synonyms	1,1,2-Trifluoro-2-(fluorosulfonyl)ethene; 2-(Fluorosulfonyl)-1,1,2-trifluoroethene; Trifluorovinylsulfonyl Fluoride; TfE-F; 1,1,2-Trifluoro-2-(fluorosulfonyl)ethylene; Perfluorovinylsulfonyl Fluoride (common name); TFESF; Vinylsulfonyl Fluoride, 1,1,2-trifluoro-
EINECS	211-685-9

Quality Control

Our Trifluoroethenesulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.