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Difluoromethyldimethylamine CAS NO 683-81-8


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CAS No.:683-81-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Difluoromethyldimethylamine is a versatile fluorinated amine building block with significant utility in advanced chemical synthesis. Its value lies in its ability to introduce the difluoromethyl group, a key motif for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate for creating novel active ingredients.

Application

  • Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for introducing fluorine atoms to improve drug potency and metabolic stability.
  • Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the difluoromethyl group enhances biological activity.
  • Fluorinated Material Precursor: Serves as a starting material for synthesizing specialty fluorinated polymers, surfactants, and liquid crystals.
  • Organic Synthesis Reagent: Employed in nucleophilic substitution and other reactions to incorporate the -CF2H moiety into complex organic frameworks.
  • Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new fluorination methodologies and novel compound libraries.

Basic Information

Product Name Difluoromethyldimethylamine
CAS No. 683-81-8
Molecular Formula C3H7F2N
Molecular Weight 95.09 g/mol
Synonyms N,N-Dimethyl-1,1-difluoromethanamine; Dimethylaminodifluoromethane; 1,1-Difluoro-N,N-dimethylmethanamine; (Difluoromethyl)dimethylamine; N,N-Dimethyldifluoromethylamine; Difluoromethyl dimethyl amine; DFMDA
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Quality Control

Our Difluoromethyldimethylamine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for every shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from incompatible materials such as strong acids and strong bases. Due to its highly volatile nature, keep containers tightly sealed and handle in a fume hood. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms
Assay (GC) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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