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Methyl2,3,3,3-Tetrafluoro-2-(Fluorosulfonyl)Propionate CAS NO 663-78-5


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CAS No.:663-78-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Methyl2,3,3,3-Tetrafluoro-2-(Fluorosulfonyl)Propionate is a specialized fluorinated building block of significant interest in advanced chemical synthesis. Its unique structure, featuring both a fluorosulfonyl and a tetrafluoropropyl ester group, makes it a valuable precursor for introducing perfluoroalkyl ether moieties. This compound is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors. It enables the synthesis of novel molecules with enhanced metabolic stability and physicochemical properties.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) with fluorinated ether segments, potentially improving bioavailability and patent life.
  • Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where fluorination can enhance activity and environmental profile.
  • Advanced Material Precursor: Serves as a monomer or modifier in the development of specialty polymers, including fluorinated elastomers and high-performance coatings with chemical and thermal resistance.
  • Lithium-Ion Battery Electrolyte Additive: Investigated for use in formulating novel electrolyte salts (e.g., fluorosulfonyl imides) to improve battery performance and safety.
  • Organic Synthesis Reagent: Employed in academic and industrial research for introducing the -SO2F group and fluorinated chains into complex organic molecules.

Basic Information

Product Name Methyl2,3,3,3-Tetrafluoro-2-(Fluorosulfonyl)Propionate
CAS No. 663-78-5
Molecular Formula C5H3F5O4S
Molecular Weight 254.13 g/mol
Synonyms Methyl 2-(Fluorosulfonyl)-3,3,3-trifluoropropionate; Methyl 3,3,3-Trifluoro-2-(fluorosulfonyl)propionate; 2-(Fluorosulfonyl)-3,3,3-trifluoropropionic Acid Methyl Ester; Methyl Perfluoropropanesulfonate Derivative; Methyl α-(Fluorosulfonyl)-β,β,β-trifluoropropionate; Propanoic acid, 2-(fluorosulfonyl)-3,3,3-trifluoro-, methyl ester; MFSP Ester
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Quality Control

Every batch of Methyl2,3,3,3-Tetrafluoro-2-(Fluorosulfonyl)Propionate is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by GC or HPLC), identity confirmation (by IR and/or NMR), and impurity profiles. Our quality system is designed to support cGMP and ISO 9001 standards for traceability and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to reference spectrum
Assay (GC/HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Related Substances (GC/HPLC) Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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