Description

Ethyl Pentafluoropropionylacetate is a high-purity fluorinated organic ester, a key building block in advanced chemical synthesis. Its value lies in the unique reactivity and properties imparted by the pentafluoropropionyl group, enabling the introduction of fluorine into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors who require precise fluorination to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in creating advanced fluorinated pesticides and herbicides, leveraging fluorine's ability to improve lipophilicity and environmental persistence.
• Material Science Research: Serves as a precursor for fluorinated polymers, liquid crystals, and coatings, contributing to enhanced chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, condensations, and as a source of the pentafluoropropionyl moiety in complex molecule construction for R&D.
• Fluorine-19 NMR Reagent: Can be utilized as a chemical shift reference or tagging agent in spectroscopic analysis due to its distinct fluorine signature.

Basic Information

Product Name	Ethyl Pentafluoropropionylacetate
CAS No.	663-35-4
Molecular Formula	C7H7F5O3
Molecular Weight	234.12 g/mol
Synonyms	Ethyl 4,4,4,5,5,5-hexafluoro-3-oxopentanoate; Ethyl 2-(pentafluoroethyl)-3-oxobutanoate; 3-Oxopentanoic acid, 4,4,4,5,5,5-hexafluoro-, ethyl ester; Pentafluoropropionylacetic acid ethyl ester; Ethyl (pentafluoroethyl)acetoacetate; Ethyl 4,4,4,5,5,5-hexafluoroacetoacetate; Hexafluoroacetylacetone ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl Pentafluoropropionylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical properties is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.