Description

2-Bromo-2'-Fluoroacetophenone is a versatile and highly reactive halogenated aromatic ketone, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of both bromine and fluorine atoms on the acetophenone scaffold, enabling precise chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated or brominated aromatic systems for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve compound efficacy and environmental profile.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic processes.
• Fluorine Chemistry Studies: A valuable reagent for investigating nucleophilic substitution reactions and the effects of fluorine substituents on aromatic reactivity.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other performance chemicals.

Basic Information

Product Name	2-Bromo-2'-Fluoroacetophenone
CAS No.	655-15-2
Molecular Formula	C8H6BrFO
Molecular Weight	217.04 g/mol
Synonyms	2'-Fluoro-2-bromoacetophenone; 1-(2-Fluorophenyl)-2-bromoethanone; α-Bromo-2'-fluoroacetophenone; 2-Bromo-1-(2-fluorophenyl)ethan-1-one; o-Fluoro-α-bromoacetophenone; 2-Bromo-2-fluoroacetophenone; Bromo(2-fluorophenyl)methanone
EINECS	Contact for details

Quality Control

Our 2-Bromo-2'-Fluoroacetophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.