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Isosorbide CAS NO 652-67-5


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CAS No.:652-67-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Isosorbide is a versatile, bio-based diol derived from renewable starch sources, serving as a key building block for sustainable polymers and specialty chemicals. Its rigid V-shaped molecular structure imparts unique properties, making it a valuable, non-toxic alternative to petrochemical-derived intermediates. This product is essential for industries focused on green chemistry, including polymer manufacturing, pharmaceuticals, and personal care, where performance and environmental responsibility are paramount.

Application

  • Polymer Industry: A crucial monomer for producing polycarbonates (PC), polyesters (PET, PTT), and polyurethanes (PUR), enhancing thermal stability, clarity, and rigidity.
  • Pharmaceuticals: Used as an excipient and as a starting material for active pharmaceutical ingredients (APIs), notably in cardiovascular medications like isosorbide dinitrate and mononitrate.
  • Personal Care & Cosmetics: Functions as a humectant and solvent in skin care, hair care, and cosmetic formulations, offering excellent moisture retention and low irritation.
  • Chemical Synthesis: Acts as a chiral intermediate and platform chemical for synthesizing surfactants, plasticizers, and other fine chemicals.
  • Green Solvents & Additives: Employed in the formulation of environmentally friendly solvents, coatings, and adhesive additives.

Basic Information

Product Name Isosorbide
CAS No. 652-67-5
Molecular Formula C6H10O4
Molecular Weight 146.14 g/mol
Synonyms 1,4:3,6-Dianhydro-D-glucitol; 1,4:3,6-Dianhydro-D-sorbitol; Isohexide; D-Isosorbide; (3R,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diol; Dianhydrosorbitol; NSC 407337; FEMA 4706
EINECS 211-463-1

Quality Control

Our Isosorbide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the required specifications for purity, identity, and performance. Certificates of Analysis (COA) are provided with every shipment, detailing key parameters such as assay, optical rotation, and impurity profiles. We can supply grades suitable for industrial, cosmetic, and pharmaceutical applications, with compliance support for relevant frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product quality.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms
Assay (HPLC) ≥ 98.0%
Optical Rotation +40.0° to +44.0° (c=1 in H2O)
Melting Point 60 - 65 °C
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals (as Pb) ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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Our in-house lab drives process innovation, new product development, and tailored synthesis solutions.