Description

1,1,1,5,5,5-Hexafluoro-2-Hydroxy-2-Methylpentan-4-One is a specialized fluorinated β-diketone derivative, serving as a critical building block in advanced chemical synthesis. Its unique structure, featuring a trifluoromethyl group at each end of the molecule, provides exceptional reactivity and stability for demanding applications. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to incorporate fluorine for enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs), leveraging fluorine's ability to improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, where the fluorine atoms enhance lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a chelating agent or precursor for metal-organic frameworks (MOFs) and catalysts in asymmetric synthesis.
• Specialty Polymer Monomer: Acts as a monomer or cross-linking agent for high-performance fluoropolymers with superior chemical and thermal resistance.
• Electrolyte Additive: Investigated for use in lithium-ion battery electrolytes to improve stability and performance at high voltages.
• Surface Modification Agent: Utilized to introduce fluorinated groups onto material surfaces, imparting hydrophobic and oleophobic characteristics.

Basic Information

Product Name	1,1,1,5,5,5-Hexafluoro-2-Hydroxy-2-Methylpentan-4-One
CAS No.	649-65-0
Molecular Formula	C6H4F6O2
Molecular Weight	222.09 g/mol
Synonyms	Hexafluoroacetylacetone, 1,1,1,5,5,5-Hexafluoro-2,4-pentanedione; 1,1,1,5,5,5-Hexafluoroacetylacetone; HFAcAc; HFAA; 1,1,1,5,5,5-Hexafluoro-2,4-dioxopentane; 4,4,4-Trifluoro-1-(trifluoroacetyl)-2-butanone; Perfluoroacetylacetone
EINECS	211-476-5

Quality Control

Our production of 1,1,1,5,5,5-Hexafluoro-2-Hydroxy-2-Methylpentan-4-One adheres to stringent quality management systems to ensure batch-to-batch consistency and purity. Every lot is analyzed using advanced techniques including GC, HPLC, NMR, and Karl Fischer titration. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.55 g/mL
Refractive Index (n20/D)	~1.315

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.