Description

L-Mannitol is a naturally occurring sugar alcohol (polyol) and a stereoisomer of the more common D-Mannitol. This high-purity, non-hygroscopic compound serves as a critical excipient and bulking agent in pharmaceutical formulations, valued for its chemical inertness and pleasant, cooling taste. It is essential for manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries seeking a reliable, multi-functional ingredient for solid dosage forms and diagnostic applications.

Application

• Pharmaceutical Excipient: Widely used as a diluent, bulking agent, and sweetener in chewable tablets, lozenges, and orally disintegrating tablets (ODTs).
• Diagnostic Reagents: A key component in culture media for microbiology and in various biochemical diagnostic kits.
• Food & Nutraceutical Additive: Employed as a low-calorie sweetener, texturizer, and anti-caking agent in sugar-free and diabetic-friendly products.
• Chemical Synthesis: Acts as a starting material or chiral building block in organic synthesis and the production of specialty chemicals.
• Cosmetics & Personal Care: Used as a humectant and viscosity controller in creams, lotions, and toothpaste.
• Industrial Applications: Functions in specialty resins, surfactants, and as a dust control agent.

Basic Information

Product Name	L-Mannitol
CAS No.	643-01-6
Molecular Formula	C6H14O6
Molecular Weight	182.17 g/mol
Synonyms	(-)-Mannitol; L-(-)-Mannitol; (2S,3S,4S,5S)-Hexane-1,2,3,4,5,6-hexol; Mannitol, L- form; 1,2,3,4,5,6-Hexanehexol, (2S,3S,4S,5S)-; L-Mannite
EINECS	211-394-0

Quality Control

Our L-Mannitol is produced under strict quality management systems. We offer grades compliant with major pharmacopoeial standards, including USP-NF and EP, as well as Food Chemical Codex (FCC) specifications for food applications. Every batch undergoes rigorous analytical testing to ensure identity, purity, and safety. A comprehensive Certificate of Analysis (COA) is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials and excessive heat.

Specification

Item	Specification
Appearance	White crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Specific Rotation [α]20/D	-0.10° to 0.10°
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Microbial Limits	Meets USP/EP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.