Description

3-Hydroxyglutaric Acid is a valuable dicarboxylic acid derivative with a hydroxyl functional group, offering unique reactivity for synthesis and biochemical applications. This compound serves as a critical chiral building block and metabolic intermediate, enabling the production of high-value fine chemicals and pharmaceuticals. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds or study metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly statins and other therapeutic agents.
• Biochemical Research: Used as a reference standard or substrate in metabolic studies, especially related to glutaric acidemia and mitochondrial disorders.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or co-monomer for producing biodegradable polyesters and functional polymers.
• Cosmetic Ingredients: Potential use in synthesizing skin-conditioning agents and moisturizers.
• Food & Flavor Chemistry: Investigated for use in producing flavor enhancers and food acidulants.

Basic Information

Product Name	3-Hydroxyglutaric Acid
CAS No.	638-18-6
Molecular Formula	C5H8O5
Molecular Weight	148.11 g/mol
Synonyms	3-Hydroxypentanedioic Acid; β-Hydroxyglutaric Acid; 3-Hydroxy-1,5-pentanedioic Acid; DL-3-Hydroxyglutaric Acid; (±)-3-Hydroxyglutaric Acid; 3-Hydroxyglutamate; NSC 92356
EINECS	211-342-4

Quality Control

Our 3-Hydroxyglutaric Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	115°C - 120°C
Loss on Drying	≤ 1.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.