Description

4-Chlorobutyric Acid is a versatile chlorinated carboxylic acid intermediate of significant importance in organic synthesis. Its reactive chlorine and carboxyl groups make it a valuable building block for constructing more complex molecules, offering a strategic pathway for introducing functionalized butyric acid chains. This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-purity intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing γ-aminobutyric acid (GABA) analogs or other pharmacologically active butyric acid derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the chlorobutyryl moiety is incorporated into the final molecule.
• Polymer & Material Science: Serves as a monomer or modifying agent for creating specialty polymers, coatings, and resins with tailored properties.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions, esterifications, and amide couplings to introduce a 4-chlorobutyryl group into target compounds.
• Biochemical Research: Utilized as a reagent in proteomics and metabolic pathway studies, often for modifying peptides or probing enzyme activity.
• Liquid Crystal & Electronic Chemicals: Acts as an intermediate in the synthesis of advanced materials for display and semiconductor applications.

Basic Information

Product Name	4-Chlorobutyric Acid
CAS No.	627-00-9
Molecular Formula	C4H7ClO2
Molecular Weight	122.55 g/mol
Synonyms	4-Chlorobutanoic Acid; γ-Chlorobutyric Acid; NSC 9375; Butyric acid, 4-chloro-; 4-Chloro-butanoic acid; ω-Chlorobutyric acid; 4-Chlorobutyric acid (6CI,7CI,8CI)
EINECS	210-966-8

Quality Control

Our 4-Chlorobutyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay, impurity profiling, and identity confirmation, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 15-25°C. The product is a strong acid/organic solvent and should be handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4520 - 1.4560
Density (20°C)	1.25 - 1.29 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.