Description

1-Chloro-3-Iodobenzene is a versatile halogenated aromatic compound that serves as a critical building block in advanced organic synthesis. Its distinct molecular structure, featuring both chlorine and iodine substituents, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for Suzuki-Miyaura and other cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where specific halogenated aromatic cores are required.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic semiconductors, liquid crystals, and specialty polymers.
• Chemical Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new catalytic processes and constructing complex molecular architectures.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Fine Chemical Production: Intermediate for manufacturing dyes, pigments, and other high-value specialty chemicals.

Basic Information

Item	Detail
Product Name	1-Chloro-3-Iodobenzene
CAS No.	625-99-0
Molecular Formula	C6H4ClI
Molecular Weight	238.45 g/mol
Synonyms	3-Chloroiodobenzene; m-Chloroiodobenzene; 1-Iodo-3-chlorobenzene; 3-Iodochlorobenzene; (3-Chlorophenyl)iodide; Benzene, 1-chloro-3-iodo-; m-Iodochlorobenzene; 625-99-0
EINECS	210-915-8

Quality Control

Our 1-Chloro-3-Iodobenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR analysis, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles to meet the stringent requirements of our global B2B clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and metals. Recommended storage temperature is between 15°C and 25°C. The product is compatible with strong acid/organic solvent environments but should be handled with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.95 g/mL
Boiling Point	~227-228 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.