Description

trans-Methyl Crotonate CAS NO 623-43-8 is a high-purity, unsaturated ester characterized by its distinct trans-configuration. This compound serves as a versatile and valuable chemical intermediate and building block in advanced organic synthesis. It is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical sectors seeking reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring an α,β-unsaturated ester moiety.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Flavor and Fragrance Ingredient: Serves as a precursor for esters that contribute to fruity and complex aroma profiles.
• Polymer Chemistry: Acts as a monomer or co-monomer in specialty polymerizations, including for coatings and adhesives.
• Organic Synthesis Reagent: Employed in Michael additions, Diels-Alder reactions, and other carbon-carbon bond-forming transformations.
• Research & Development: A critical reagent for medicinal chemistry and process development in laboratory-scale and pilot-scale operations.

Basic Information

Product Name	trans-Methyl Crotonate
CAS No.	623-43-8
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	trans-2-Butenoic Acid Methyl Ester; Methyl trans-2-Butenoate; Methyl (E)-2-Butenoate; (E)-2-Butenoic Acid Methyl Ester; Methyl Crotonate (trans-); Crotonic Acid Methyl Ester (trans-); Methyl β-Methylacrylate; 2-Butenoic Acid, Methyl Ester, (2E)-
EINECS	210-793-7

Quality Control

Our trans-Methyl Crotonate is produced under stringent quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and isomeric integrity. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent evaporation and moisture absorption.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Isomeric Purity (trans-)	≥ 99.0%
Water Content (KF)	≤ 0.1%
Refractive Index (20°C)	1.424 - 1.428
Density (20°C)	0.945 - 0.955 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.