Description

3-Nitrophenylacetonitrile is a versatile aromatic nitrile building block of significant importance in advanced organic synthesis. Its structure, featuring both a reactive nitrile group and an electron-withdrawing nitro substituent, makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing heterocyclic structures or aniline derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the nitrophenyl moiety is a common structural motif.
• Dye and Pigment Manufacturing: Serves as a building block for azo dyes and other complex colorants, leveraging the nitro group for color development and stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry research.
• Material Science Research: Acts as a monomer or modifier in the synthesis of polymers and advanced organic materials with specific electronic properties.
• Chemical Research & Development: A valuable reagent for exploring novel organic reactions, including nucleophilic substitution and reduction chemistry.

Basic Information

Product Name	3-Nitrophenylacetonitrile
CAS No.	621-50-1
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	(3-Nitrophenyl)acetonitrile; 2-(3-Nitrophenyl)acetonitrile; m-Nitrophenylacetonitrile; 3-Nitrobenzyl cyanide; (m-Nitrophenyl)acetonitrile; 3-Nitrobenzeneacetonitrile; 621-50-1; NSC 406106
EINECS	210-690-8

Quality Control

Our 3-Nitrophenylacetonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, GC, and NMR analyses. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.