Description

1-(4-Fluorophenyl)Butan-2-One is a versatile fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its core value lies in providing a reactive carbonyl group adjacent to a fluorinated phenyl ring, enabling precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the bioisosteric properties of the fluorine atom.
• Agrochemical Research: Used in constructing novel herbicides, fungicides, and insecticides where the fluorophenyl moiety can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Fine Chemical Synthesis: Employed in multi-step organic reactions, including Grignard additions, reductions, and condensation reactions, to create more complex fluorinated structures.
• Academic & R&D Laboratories: A valuable reagent for methodological studies and exploring new synthetic pathways involving fluorinated ketones.

Basic Information

Product Name	1-(4-Fluorophenyl)Butan-2-One
CAS No.	620-97-3
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	4'-Fluorobutyrophenone; 4-Fluorobutyrophenone; 1-(4-Fluorophenyl)-2-butanone; p-Fluorobutyrophenone; Butan-2-one, 1-(4-fluorophenyl)-; 4-Fluorophenyl ethyl ketone; 620-97-3; NSC 406925
EINECS	210-663-6

Quality Control

Our production of 1-(4-Fluorophenyl)Butan-2-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity essential for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and MS to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.