Description

2-Bromo-1-(4'-Chloro-Biphenyl-4-Yl)-Ethanone is a high-purity, specialized organic building block of significant interest in advanced chemical synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research and development. It is essential for chemists and process development scientists in the fine chemical, pharmaceutical, and life science industries who require reliable, high-quality raw materials for innovative API and active ingredient synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those with biphenyl or diaryl ketone scaffolds.
• Agrochemical Research: Used in the development and production of advanced herbicides, fungicides, and pesticides.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand Synthesis: Valuable intermediate for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for biological target investigation.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	2-Bromo-1-(4'-Chloro-Biphenyl-4-Yl)-Ethanone
CAS No.	613-34-3
Molecular Formula	C14H10BrClO
Molecular Weight	309.59 g/mol
Synonyms	2-Bromo-1-(4'-chloro[1,1'-biphenyl]-4-yl)ethanone; 4'-Chloro-4-bromoacetylbiphenyl; 2-Bromo-4'-(4-chlorophenyl)acetophenone; 1-(4'-Chlorobiphenyl-4-yl)-2-bromoethanone; p-Chlorophenyl 4-Bromoacetylphenyl Ether (common misnomer); α-Bromo-4'-(4-chlorophenyl)acetophenone; 2-Bromo-1-(4-chlorobiphenyl-4-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4'-Chloro-Biphenyl-4-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.