Description

Dl -α-Hydroxyisovaleric Acid CAS NO 600-37-3 is a versatile chiral hydroxy acid derivative, serving as a critical building block in organic synthesis. Its value lies in its bifunctional structure, containing both a carboxylic acid and a hydroxyl group, which enables its use in constructing complex molecules for high-value applications. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing drugs targeting metabolic and neurological pathways.
• Agrochemical Synthesis: Used in the production of advanced herbicides and plant growth regulators, leveraging its structural motif for biological activity.
• Flavor and Fragrance Precursor: Serves as a starting material for creating specific lactones and esters that contribute to complex flavor and aroma profiles.
• Biochemical Research: Employed in studies of enzyme mechanisms and metabolic processes, such as those involving branched-chain amino acid catabolism.
• Polymer Modification: Acts as a monomer or cross-linking agent for synthesizing specialty polyesters with tailored properties.
• Cosmetic Ingredient Synthesis: A precursor for α-hydroxy acid (AHA) derivatives used in skincare formulations for exfoliation and moisturization.

Basic Information

Product Name	Dl -α-Hydroxyisovaleric Acid
CAS No.	600-37-3
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	DL-2-Hydroxy-3-methylbutanoic acid; (±)-2-Hydroxy-3-methylbutyric acid; 2-Hydroxyisovaleric acid; α-Hydroxyisovaleric acid; 3-Methyl-2-hydroxybutanoic acid; Hydroxymethylbutyric acid; HMB (in specific contexts); Racemic 2-hydroxy-3-methylbutanoic acid
EINECS	209-983-7

Quality Control

Our Dl -α-Hydroxyisovaleric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing specific results for identity, assay, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Racemic mixture (DL ratio ~50:50)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.