Description

4-(Benzenesulfonyl)Benzaldehyde is a versatile aromatic aldehyde derivative featuring a sulfonyl linker, making it a valuable bifunctional building block in advanced organic synthesis. This compound is particularly significant for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing sulfonamide or diaryl sulfone motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where the sulfonyl group confers specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel ligands and organocatalysts used in asymmetric synthesis and metal-catalyzed reactions.
• Polymer and Material Science: Employed in the synthesis of specialty polymers, dyes, and photoactive materials due to its reactive aldehyde and stable sulfone groups.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Organic Synthesis Building Block: Utilized in condensation reactions, such as the Knoevenagel condensation, to form α,β-unsaturated carbonyl compounds for further functionalization.

Basic Information

Product Name	4-(Benzenesulfonyl)Benzaldehyde
CAS No.	66-39-7
Molecular Formula	C₁₃H₁₀O₃S
Molecular Weight	246.28 g/mol
Synonyms	4-(Phenylsulfonyl)benzaldehyde; [1,1'-Biphenyl]-4-carboxaldehyde, 4'-sulfo-; p-(Phenylsulfonyl)benzaldehyde; 4-(Benzenesulphonyl)benzaldehyde; 4-(Phenylsulphonyl)benzaldehyde; Benzaldehyde, 4-(phenylsulfonyl)-; 4-Benzenesulfonylbenzaldehyde
EINECS	200-622-5

Quality Control

Our 4-(Benzenesulfonyl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	142 - 146 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.