Description

5-Methoxythiophene-2-Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a protected boronic acid derivative, essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a pivotal method for constructing complex molecules with precision. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing thiophene-containing drug candidates, including potential kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the 5-methoxythiophene moiety.
• Material Science Research: Serves as a precursor for creating conjugated polymers and organic electronic materials (OLEDs, OFETs) due to the thiophene backbone.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.
• Academic & Industrial R&D: Fundamental building block for methodological development in cross-coupling chemistry and heterocyclic compound library synthesis.

Basic Information

Product Name	5-Methoxythiophene-2-Boronic Acid Pinacol Ester
CAS No.	596819-12-4
Molecular Formula	C11H17BO3S
Molecular Weight	240.13 g/mol
Synonyms	5-Methoxy-2-thienylboronic acid pinacol ester; 2-(5-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 5-Methoxythiophene-2-boronic acid neopentyl glycol ester (common name); 2-(5-Methoxythiophen-2-yl)-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-; 5-Methoxy-2-thiopheneboronic acid pinacol ester; Pinacol (5-Methoxy-2-thienyl)boronate; 5-Methoxy-2-thienyl-B(pin)
EINECS	Contact for details

Quality Control

Our 5-Methoxythiophene-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B) and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements in advanced R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.