Description

3-Bromo-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-Yl)Benzene is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific biphenyl motifs.
• Material Science: Serves as a precursor for organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Research: A versatile reagent in academic and industrial R&D for constructing complex aromatic and heteroaromatic systems.
• Ligand & Catalyst Development: Employed in the synthesis of novel phosphine or N-heterocyclic carbene (NHC) ligands for catalysis.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, dyes, and pigments.

Basic Information

Product Name	3-Bromo-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-Yl)Benzene
CAS No.	594823-67-3
Molecular Formula	C12H16BBrO2
Molecular Weight	283.97 g/mol
Synonyms	(3-Bromophenyl)boronic acid pinacol ester; 3-Bromophenylboronic acid pinacol ester; 1-Bromo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; 3-Bromobenzeneboronic acid pinacol ester; m-Bromophenylboronic acid pinacol ester; Pinacol (3-bromophenyl)boronate; 3-Bromo phenyl boronic acid pinacol ester; 3-BPBpin
EINECS	Contact for details

Quality Control

Our 3-Bromo-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-Yl)Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to confirm identity, potency, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening a new container to prevent hydrolysis and maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.