Description

2-Propenamide,2-Cyano-n-[2-(1H-Indol-3-Yl)Ethyl]-3-[4-(Methylthio)Phenyl]-(9Ci) is a specialized acrylamide derivative of significant interest in advanced organic synthesis and pharmaceutical research. Its molecular architecture, featuring indole and methylthiophenyl moieties, makes it a valuable high-purity building block for developing novel bioactive compounds. This product is primarily targeted at research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in medicinal chemistry and the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies due to its unique indole-acrylamide hybrid structure.
• Bioconjugation & Probe Development: The reactive acrylamide group enables its use in creating fluorescent probes or affinity labels for biochemical studies.
• Advanced Material Synthesis: Potential monomer or cross-linker in the development of specialty polymers with specific optical or electronic properties.
• Academic & Industrial R&D: Employed in exploratory synthetic chemistry for constructing novel heterocyclic libraries.

Basic Information

Product Name	2-Propenamide,2-Cyano-n-[2-(1H-Indol-3-Yl)Ethyl]-3-[4-(Methylthio)Phenyl]-(9Ci)
CAS No.	593273-45-1
Molecular Formula	C21H19N3OS
Molecular Weight	361.46 g/mol
Synonyms	2-Cyano-N-[2-(1H-indol-3-yl)ethyl]-3-[4-(methylthio)phenyl]prop-2-enamide; 3-[4-(Methylthio)phenyl]-2-cyano-N-[2-(1H-indol-3-yl)ethyl]acrylamide; 2-Cyano-3-(4-methylthiophenyl)-N-(2-indol-3-ylethyl)acrylamide; Acrylamide, 2-cyano-N-[2-(1H-indol-3-yl)ethyl]-3-[4-(methylthio)phenyl]-; (2E)-2-Cyano-3-[4-(methylsulfanyl)phenyl]-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.