Description

5-(Trifluoromethyl)-1H-Pyrazole-3-Carbaldehyde is a versatile fluorinated pyrazole derivative, a high-value building block prized for its trifluoromethyl group and aldehyde functionality. This compound is critical for introducing the metabolically stable CF3 moiety and a reactive formyl handle into complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of small molecule drugs, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands, polymers, and organic electronic materials.
• Chemical Biology: Employed in the synthesis of probes and molecular tools due to its reactive aldehyde group for bioconjugation.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom chemical synthesis and scale-up projects.

Basic Information

Product Name	5-(Trifluoromethyl)-1H-Pyrazole-3-Carbaldehyde
CAS No.	591234-14-9
Molecular Formula	C5H3F3N2O
Molecular Weight	164.09 g/mol
Synonyms	1H-Pyrazole-3-carboxaldehyde, 5-(trifluoromethyl)-; 3-Formyl-5-(trifluoromethyl)-1H-pyrazole; 5-(Trifluoromethyl)-1H-pyrazole-3-carboxaldehyde; 5-Trifluoromethyl-1H-pyrazole-3-carbaldehyde; 5-Trifluoromethylpyrazole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1H-Pyrazole-3-Carbaldehyde is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.