Description

2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, protected aniline boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for developing active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in creating biaryl and heterobiaryl structures common in many therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the boronic ester group allows for the introduction of specific aromatic subunits.
• Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional organic materials requiring tailored aromatic architectures.
• Chemical Biology & Probe Development: Serves as a versatile intermediate for creating molecular probes and labeled compounds used in diagnostic and biochemical research.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in cross-coupling chemistry and the exploration of new synthetic pathways.
• Ligand & Catalyst Preparation: Can be utilized in the synthesis of specialized ligands for catalysis or as a precursor for metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	590418-05-6
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	4-Amino-3-methylphenylboronic acid pinacol ester; 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; 3-Methyl-4-(pinacolatoboryl)aniline; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylaniline; 2-Methyl-4-boronic acid pinacol ester aniline; 4-Amino-3-methylbenzeneboronic acid pinacol ester; PINACOL 2-METHYL-4-AMINOPHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.