Description

3-Methyl-4-Nitro-Phenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecular architectures. The pinacol ester group enhances stability, making it a preferred reagent for demanding synthetic sequences.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and candidate molecules, particularly those containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific substituted phenyl groups.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs or OFETs, where precise conjugation is needed.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and labeled compounds for studying biological pathways and diagnostics.

Basic Information

Product Name	3-Methyl-4-Nitro-Phenylboronic Acid Pinacol Ester
CAS No.	590418-04-5
Molecular Formula	C₁₃H₁₈BNO₄
Molecular Weight	263.10 g/mol
Synonyms	4-Nitro-3-methylbenzeneboronic acid pinacol ester; (3-Methyl-4-nitrophenyl)boronic acid pinacol ester; 2-(3-Methyl-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methyl-4-nitrophenylboronic acid pinacol ester; PINACOL 3-METHYL-4-NITROPHENYLBORONATE
EINECS	Contact for details

Quality Control

Every batch of 3-Methyl-4-Nitro-Phenylboronic Acid Pinacol Ester is manufactured and tested under strict quality management protocols. We guarantee high chemical purity and lot-to-lot consistency, which is essential for reproducible cross-coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.