Description

2-Bromo-5-Ethoxy-4-Isopropoxybenzonitrile is a high-purity, multi-functional aromatic nitrile derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique substitution pattern, which provides distinct reactivity for constructing complex molecular architectures. This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the bromine and ether functionalities for bioactivity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing specialized aromatic cores used in electronic display technologies and organic light-emitting diodes.
• Ligand & Catalyst Development: The nitrile and bromine groups make it a valuable scaffold for creating novel ligands in transition metal catalysis and organocatalysis.
• Polymer Modification: Employed to introduce functional aromatic units into polymer backbones to alter thermal, optical, or mechanical properties.
• Academic & Contract Research: An essential reagent for methodological development in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	2-Bromo-5-Ethoxy-4-Isopropoxybenzonitrile
CAS No.	590355-61-6
Molecular Formula	C₁₂H₁₄BrNO₂
Molecular Weight	284.15 g/mol
Synonyms	4-Isopropoxy-2-bromo-5-ethoxybenzonitrile; Benzonitrile, 2-bromo-5-ethoxy-4-(1-methylethoxy)-; 2-Bromo-5-ethoxy-4-isopropoxybenzonitrile; 5-Ethoxy-2-bromo-4-isopropoxybenzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Ethoxy-4-Isopropoxybenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing batch-specific results against agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.