Description

Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-(2-Thienylmethyl)- (9Ci) is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring fused thiophene and benzothiophene rings with halogen and amide substituents, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily utilized by research institutions and pharmaceutical R&D departments engaged in the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Acts as a building block for organic electronic materials, such as organic semiconductors and charge-transport materials, due to its conjugated thiophene-based system.
• Chemical Biology Probe Development: Employed in creating molecular probes to study enzyme function and biological pathways, where its structure can be modified for specific targeting.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	Benzo[B]Thiophene-2-Carboxamide, 3-Chloro-4-Fluoro-n-(2-Thienylmethyl)- (9Ci)
CAS No.	588675-31-4
Molecular Formula	C14H9ClFNOS2
Molecular Weight	325.81 g/mol
Synonyms	3-Chloro-4-fluoro-N-(thiophen-2-ylmethyl)benzo[b]thiophene-2-carboxamide; N-((2-Thienyl)methyl)-3-chloro-4-fluorobenzo[b]thiophene-2-carboxamide; 3-Chloro-4-fluoro-N-(2-thienylmethyl)-1-benzothiophene-2-carboxamide; 588675-31-4; Benzo[b]thiophene-2-carboxamide, 3-chloro-4-fluoro-N-(2-thienylmethyl)-; 3-Chloro-4-fluoro-N-(thiophen-2-ylmethyl)benzo[b]thiophene-2-carboxamide (9CI)
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophene-2-Carboxamide derivative is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure consistent high quality and batch-to-batch reproducibility. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.