Description

tert-Butyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-9H-Thioxanthen-2-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate featuring a boronic ester pinacol group, making it a critical building block for modern synthetic chemistry. Its value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are essential for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and organic electronic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those with a thioxanthene core structure.
• Suzuki-Miyaura Cross-Coupling Reactions: The boronic ester functionality enables efficient carbon-carbon bond formation for constructing biaryl and heterobiaryl systems.
• Organic Light-Emitting Diode (OLED) Materials Research: Used in the development of novel electron-transport or host materials due to the thioxanthene scaffold.
• Agrochemical Synthesis: Acts as a building block for creating new molecules with potential herbicidal or insecticidal activity.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry and material science.
• Ligand and Catalyst Development: The structure can be modified to create novel ligands for transition metal catalysis.

Basic Information

Product Name	tert-Butyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-9H-Thioxanthen-2-Ylcarbamate
CAS No.	587871-47-4
Molecular Formula	C24H30BNO4S
Molecular Weight	439.37 g/mol
Synonyms	2-[[(1,1-Dimethylethoxy)carbonyl]amino]-9H-thioxanthene-5-boronic acid pinacol ester; 5-[(tert-Butoxycarbonyl)amino]-9H-thioxanthene-2-boronic acid pinacol ester; tert-Butyl N-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-9H-thioxanthen-2-yl]carbamate; 587871-47-4; BOC-protected thioxanthene boronic ester; 2-(Boc-amino)-9H-thioxanthene-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-9H-Thioxanthen-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.