Description

2-tert-Butyl-7-Fluoro-1H-Indole-3-Carbaldehyde is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both a tert-butyl group and a fluorine atom, makes it a valuable precursor for creating novel compounds with tailored properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science Precursor: Serves as a building block for advanced organic materials, including organic light-emitting diodes (OLEDs) and functional dyes, due to its conjugated indole core.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals for clients.

Basic Information

Product Name	2-tert-Butyl-7-Fluoro-1H-Indole-3-Carbaldehyde
CAS No.	586949-71-5
Molecular Formula	C₁₃H₁₄FNO
Molecular Weight	219.26 g/mol
Synonyms	7-Fluoro-2-tert-butyl-1H-indole-3-carboxaldehyde; 2-(tert-Butyl)-7-fluoro-1H-indole-3-carbaldehyde; 2-tert-Butyl-7-fluoroindole-3-carboxaldehyde; 1H-Indole-3-carboxaldehyde, 2-(1,1-dimethylethyl)-7-fluoro-; 586949-71-5; 7-Fluoro-2-(tert-butyl)-1H-indole-3-carbaldehyde
EINECS	Contact for details

Quality Control

Our 2-tert-Butyl-7-Fluoro-1H-Indole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.