Description

5-Chloro-2-[[[(3-Methyl-4-Nitrobenzoyl)Amino]Thioxomethyl]Amino]-Benzoic Acid is a specialized organic intermediate featuring a complex molecular architecture that combines benzoic acid, thiourea, and nitroarene functionalities. This compound is valued for its role as a key building block in the synthesis of advanced chemical entities, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for constructing novel molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging its nitro and chlorinated aromatic structure.
• Chemical Biology Probe: Acts as a scaffold or a tagging agent in the design of molecular probes for studying biological pathways and protein interactions.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized azo dyes or pigments due to the presence of nitro and amino-thioxomethyl groups.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or optical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects requiring this precise molecular framework.

Basic Information

Product Name	5-Chloro-2-[[[(3-Methyl-4-Nitrobenzoyl)Amino]Thioxomethyl]Amino]-Benzoic Acid
CAS No.	586392-43-0
Molecular Formula	C16H12ClN3O5S
Molecular Weight	393.80 g/mol
Synonyms	5-Chloro-2-[[[(3-methyl-4-nitrobenzoyl)amino]thioxomethyl]amino]benzoic acid; 2-[[[(3-Methyl-4-nitrobenzoyl)amino]carbothioyl]amino]-5-chlorobenzoic acid; 5-Chloro-2-[(3-methyl-4-nitrobenzoyl)thioureido]benzoic acid; Benzoic acid, 5-chloro-2-[[[(3-methyl-4-nitrobenzoyl)amino]thioxomethyl]amino]-; 586392-43-0; (3-Methyl-4-nitrobenzoyl)thiourea derivative of 5-chloroanthranilic acid
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-2-[[[(3-Methyl-4-Nitrobenzoyl)Amino]Thioxomethyl]Amino]-Benzoic Acid adheres to stringent in-process controls and final batch testing to ensure identity, purity, and consistency. We employ advanced analytical techniques including HPLC, NMR, and MS for comprehensive characterization. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment, supporting your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfer should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.