Description

4-Bromo-2,3-Difluorobenzaldehyde is a versatile halogenated and fluorinated aromatic aldehyde building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents adjacent to the reactive aldehyde group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as in materials science for developing specialty polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring difluorobenzene and bromoarene motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine and bromine atoms can enhance lipophilicity and target binding.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in advanced display technologies.
• Organic Electronic Materials: Employed in the research and production of organic semiconductors and charge-transport materials for OLEDs and photovoltaic cells.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form complex biaryl structures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and creating custom chemical libraries for screening.

Basic Information

Product Name	4-Bromo-2,3-Difluorobenzaldehyde
CAS No.	586382-05-0
Molecular Formula	C7H3BrF2O
Molecular Weight	221.00 g/mol
Synonyms	2,3-Difluoro-4-bromobenzaldehyde; 4-Bromo-2,3-difluorobenzenecarboxaldehyde; Benzaldehyde, 4-bromo-2,3-difluoro-; 586382-05-0; 4-Bromo-2,3-difluoro benzaldehyde; 4-Br-2,3-F2C6H2CHO
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-2,3-Difluorobenzaldehyde is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.