Description

2-Methyl-1-[3-(Trifluoromethyl)Phenyl]Propan-1-One is a specialized fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity of the ketone group combined with the electron-withdrawing and lipophilicity-enhancing properties of the trifluoromethyl substituent. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex molecules, particularly those requiring the incorporation of a trifluoromethylphenyl moiety to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel fluorinated polymers, liquid crystals, and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in chemical manufacturing.

Basic Information

Product Name	2-Methyl-1-[3-(Trifluoromethyl)Phenyl]Propan-1-One
CAS No.	586369-93-9
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	1-[3-(Trifluoromethyl)phenyl]-2-methylpropan-1-one; 2-Methyl-1-(3-trifluoromethylphenyl)propan-1-one; 3'-Trifluoromethylisobutyrophenone; α,α-Dimethyl-3-(trifluoromethyl)benzeneacetone; m-Trifluoromethylisobutyrophenone; 3-(Trifluoromethyl)isobutyrophenone; Benzeneacetone, α,α-dimethyl-3-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2-Methyl-1-[3-(Trifluoromethyl)Phenyl]Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.