Description

2,2-Dimethyl-4'-Trifluoromethylpropiophenone is a high-purity, specialized aromatic ketone building block featuring a trifluoromethyl group. This compound is valued for its role as a critical intermediate in the synthesis of advanced pharmaceutical and agrochemical active ingredients. It is primarily sought by research and development chemists and process engineers in the fine chemical, pharmaceutical, and crop protection industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides and fungicides, leveraging the stability and lipophilicity imparted by the trifluoromethyl group.
• Material Science Research: Used in the development of specialty polymers and liquid crystals where the specific steric and electronic properties of the molecule are advantageous.
• Organic Synthesis & Catalysis: An important substrate in methodological studies and asymmetric catalysis for constructing complex, fluorinated molecular architectures.

Basic Information

Product Name	2,2-Dimethyl-4'-Trifluoromethylpropiophenone
CAS No.	586346-65-8
Molecular Formula	C12H13F3O
Molecular Weight	230.23 g/mol
Synonyms	1-(4-(Trifluoromethyl)phenyl)-2,2-dimethylpropan-1-one; 2,2-Dimethyl-1-[4-(trifluoromethyl)phenyl]-1-propanone; 4'-Trifluoromethyl-2,2-dimethylpropiophenone; α,α-Dimethyl-4-(trifluoromethyl)benzeneacetone; p-(Trifluoromethyl)desoxybenzoin, 2,2-dimethyl-; Propiophenone, 2,2-dimethyl-4'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 2,2-Dimethyl-4'-Trifluoromethylpropiophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.