Description

Methyl 3-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Benzoate is a valuable boronic ester derivative, specifically a protected boronic acid, widely used as a key synthetic intermediate. Its primary value lies in enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing biaryl and other carbon-carbon bonds under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it facilitates the development of complex molecules and active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing biphenyl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a monomer or precursor for creating novel organic electronic materials, such as polymers for OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A go-to reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Methyl 3-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Benzoate
CAS No.	585524-77-2
Molecular Formula	C14H19BO4
Molecular Weight	262.11 g/mol
Synonyms	3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)benzoic acid methyl ester; Methyl 3-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate; 3-(5,5-Dimethyl-1,3,2-dioxaborinan-2-yl)methyl benzoate; Benzoic acid, 3-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)-, methyl ester; MIDA Boronate Ester of Methyl 3-Boronobenzoate; 3-Carbomethoxyphenylboronic acid MIDA ester
EINECS	Contact for details

Quality Control

Our Methyl 3-(5,5-Dimethyl-1,3,2-Dioxaborinan-2-Yl)Benzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening a new container to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.