Description

6-(3-Fluorophenyl)-Nicotinic Acid CAS NO 582325-22-2 is a high-purity fluorinated nicotinic acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the fluorine substituent, enabling precise molecular modifications essential for developing high-performance materials and active compounds. This intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical sectors, where it is utilized to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug discovery programs.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorophenyl moiety can improve biological activity and environmental stability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes for studying enzyme mechanisms and biological pathways.
• Advanced Material Development: A starting material for synthesizing functionalized polymers and liquid crystals with specific optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated aromatic compounds.

Basic Information

Product Name	6-(3-Fluorophenyl)-Nicotinic Acid
CAS No.	582325-22-2
Molecular Formula	C12H8FNO2
Molecular Weight	217.20 g/mol
Synonyms	3-Fluoro-5-pyridinecarboxylic acid, 6-(3-Fluorophenyl); 6-(3-Fluorophenyl)pyridine-3-carboxylic acid; 3-Fluoro-5-(3-fluorophenyl)pyridine-2-carboxylic acid (alternative numbering); Nicotinic acid, 6-(3-fluorophenyl)-; 582325-22-2; 3-Pyridinecarboxylic acid, 6-(3-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 6-(3-Fluorophenyl)-Nicotinic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques, including HPLC, GC, and NMR, to ensure identity, purity, and consistency meet the exacting standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed due to the compound's sensitivity to moisture (hygroscopic).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.