Description

3,5-Difluoro-Benzamidine is a high-purity, bifunctional organic building block featuring both a benzamidine core and strategically placed fluorine atoms. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where it introduces key pharmacophoric elements. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of protease inhibitors, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the amidine group and fluorine substitution.
• Chemical Biology Research: Serves as a versatile scaffold or ligand in the development of chemical probes and enzyme inhibitors for target validation studies.
• Material Science Precursor: Potential monomer or cross-linking agent in the synthesis of specialty polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	3,5-Difluoro-Benzamidine
CAS No.	582307-06-0
Molecular Formula	C7H6F2N2
Molecular Weight	156.13 g/mol
Synonyms	3,5-Difluorobenzene carboximidamide; 3,5-Difluorobenzamidine; Benzenecarboximidamide, 3,5-difluoro-; 3,5-Difluorobenzenecarboximidamide; 3,5-Difluorophenylamidine; (3,5-Difluorophenyl)methanimidamide; 582307-06-0
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-Benzamidine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.