Description

3-Nitro-trans-β-Styrylboronic Acid Pinacol Ester is a high-purity, advanced boronic ester building block crucial for modern synthetic chemistry. This compound is specifically engineered for use in cross-coupling reactions, such as the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecular architectures. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality reagents for developing new active ingredients and functional materials. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and performance.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or styrenyl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling methodologies.
• Material Science: Serves as a monomer or precursor in the creation of advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Synthesis: Enables the introduction of the 3-nitrostyryl moiety into complex molecules via robust Suzuki-Miyaura coupling reactions.
• Ligand & Catalyst Development: Utilized as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Academic & R&D: A valuable reagent for methodological development and exploratory organic synthesis in university and industrial research laboratories.

Basic Information

Product Name	3-Nitro-trans-β-Styrylboronic Acid Pinacol Ester
CAS No.	581802-25-7
Molecular Formula	C₁₈H₂₄BNO₄
Molecular Weight	329.20 g/mol
Synonyms	trans-2-(3-Nitrophenyl)vinylboronic acid pinacol ester; (E)-2-(3-Nitrostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Nitrostyrylboronic Acid Pinacol Ester; 3-Nitro-β-styrylboronic Acid Pinacol Ester; Boronic acid, B-[2-(3-nitrophenyl)ethenyl]-, 1,1-dimethylethyl ester; 581802-25-7; (E)-3-Nitrostyrylboronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 3-Nitro-trans-β-Styrylboronic Acid Pinacol Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity, purity, and isomeric composition. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with your research or production requirements. For specific purity grades or custom specifications, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Isomeric Purity (trans)	≥98.0% (by HPLC)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.