Description

2-Bromo-trans-β-Styrylboronic Acid Pinacol Ester is a high-value organoboron building block, specifically a functionalized styrylboronate ester. This compound matters for its role as a key intermediate in advanced cross-coupling reactions, enabling the precise construction of complex molecular architectures. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing novel active ingredients and functional polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a versatile coupling partner for the synthesis of substituted stilbenes and extended conjugated systems.
• Pharmaceutical Intermediate: In the research and development of potential drug candidates, particularly those requiring a brominated styryl moiety.
• Agrochemical Synthesis: For creating novel active ingredients with specific structural motifs for crop protection.
• Material Science Research: As a monomer or precursor for organic electronic materials, such as OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Serving as a precursor for sophisticated ligands used in asymmetric catalysis.
• Chemical Biology Probes: For labeling and studying biological processes due to its reactive handles (bromo and boronate).

Basic Information

Product Name	2-Bromo-trans-β-Styrylboronic Acid Pinacol Ester
CAS No.	581802-24-6
Molecular Formula	C₁₄H₁₈BBrO₂
Molecular Weight	309.01 g/mol
Synonyms	2-Bromo-trans-β-Styrylboronic Acid Pinacol Ester; (E)-2-Bromostyrylboronic Acid Pinacol Ester; trans-2-Bromostyrylboronic Acid Pinacol Ester; (E)-1-(2-Bromophenyl)-2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)ethene; 2-Bromo-trans-styrylboronic Acid Pinacol Ester; 2-Bromostyrylboronic Acid Pinacol Ester (trans); (E)-2-Bromovinylbenzeneboronic Acid Pinacol Ester; B-(2-Bromo-trans-styryl)boronic Acid Pinacol Ester
EINECS	Contact for details

Quality Control

Our 2-Bromo-trans-β-Styrylboronic Acid Pinacol Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (trans)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.