Description

1-(2-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Ethyl)-Piperidine is a sophisticated boronic ester derivative, a key intermediate in modern synthetic organic chemistry. Its value lies in its role as a protected boronic acid, offering enhanced stability and solubility for critical cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients. The CAS number for this product is 581065-57-8.

Application

This advanced chemical intermediate is primarily utilized in research and development as well as in commercial synthesis. Its applications include:

• Suzuki-Miyaura Cross-Coupling Reactions: Serving as a crucial coupling partner for the formation of carbon-carbon bonds in complex molecule synthesis.
• Pharmaceutical Intermediate: Used in the research and production of active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Agrochemical Synthesis: A building block for creating novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Used to synthesize novel ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Facilitates the creation of molecular probes for studying biological processes and drug discovery.

Basic Information

Product Name	1-(2-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Ethyl)-Piperidine
CAS No.	581065-57-8
Molecular Formula	C19H30BNO3
Molecular Weight	331.26 g/mol
Synonyms	1-(2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)ethyl)piperidine; 2-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(2-Piperidinoethoxy)phenylboronic acid pinacol ester; Pinacol [3-(2-piperidin-1-ylethoxy)phenyl]boronate; 581065-57-8; Boronic acid, B-[3-[2-(1-piperidinyl)ethoxy]phenyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 1-(2-[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Ethyl)-Piperidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for advanced intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.