Description

Benzoic Acid, 4-Methoxy-3-(Trifluoromethyl)-, Methyl Ester is a high-purity, fluorinated aromatic ester building block of significant interest in advanced chemical synthesis. This compound matters for its unique trifluoromethyl and methoxy substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used as a building block for developing advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic materials, contributing to improved performance in display and lighting technologies.
• Organic Synthesis & Catalysis: Employed in cross-coupling reactions and as a specialty reagent for introducing the 4-methoxy-3-(trifluoromethyl)benzoyl moiety into complex molecular architectures.
• Chemical Research: Used in academic and industrial R&D laboratories for studying structure-activity relationships (SAR) and developing novel synthetic methodologies.

Basic Information

Product Name	Benzoic Acid, 4-Methoxy-3-(Trifluoromethyl)-, Methyl Ester
CAS No.	576170-42-8
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	4-Methoxy-3-(trifluoromethyl)benzoic acid methyl ester; Methyl 4-methoxy-3-(trifluoromethyl)benzoate; 3-Trifluoromethyl-4-methoxy methyl benzoate; Methyl 3-(trifluoromethyl)-4-methoxybenzoate; 4-Methoxy-α,α,α-trifluoro-m-toluic acid methyl ester; Benzoic acid, 4-methoxy-3-(trifluoromethyl)-, methyl ester; 576170-42-8
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 4-Methoxy-3-(Trifluoromethyl)-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.