Description

Ethanone, 2,2,2-Trifluoro-1-[1-(2-Methoxyethyl)-1H-Pyrrol-2-Yl]- (9Ci) is a specialized trifluoromethyl ketone derivative featuring a pyrrole moiety, serving as a high-value synthetic intermediate. This compound is critical for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where the introduction of fluorine atoms is required to modulate biological activity and metabolic stability. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, crop protection, and materials science.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the discovery and synthesis of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the development of advanced polymers, coatings, and electronic materials with specific optical or surface properties.
• Chemical Biology & Probe Development: Utilized in the design of molecular probes and enzyme inhibitors for biochemical and pharmacological research due to its reactive ketone group and fluorinated structure.
• Organic Synthesis Reagent: Acts as a versatile electrophile or coupling partner in cross-coupling reactions, nucleophilic additions, and cyclization reactions to construct complex heterocyclic systems.

Basic Information

Product Name	Ethanone, 2,2,2-Trifluoro-1-[1-(2-Methoxyethyl)-1H-Pyrrol-2-Yl]- (9Ci)
CAS No.	573982-85-1
Molecular Formula	C9H10F3NO2
Molecular Weight	221.18 g/mol
Synonyms	2,2,2-Trifluoro-1-[1-(2-methoxyethyl)-1H-pyrrol-2-yl]ethanone; 1-[1-(2-Methoxyethyl)-1H-pyrrol-2-yl]-2,2,2-trifluoroethanone; 2,2,2-Trifluoro-1-(1-(2-methoxyethyl)-1H-pyrrol-2-yl)ethan-1-one; Trifluoroacetyl pyrrole derivative; 1-(1-(2-Methoxyethyl)pyrrol-2-yl)-2,2,2-trifluoroethanone; TFMPE intermediate
EINECS	Contact for details

Quality Control

Our Ethanone, 2,2,2-Trifluoro-1-[1-(2-Methoxyethyl)-1H-Pyrrol-2-Yl]- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.