Description

Benzoic Acid, 2-Amino-4-Borono-, 1-Ethyl Ester (9Ci) is a specialized boronic acid derivative, a key building block in modern synthetic chemistry. Its unique structure, featuring both an amino group and a boronic ester, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutics and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for boron-containing drugs and protease inhibitors.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key organoboron reagent for forming carbon-carbon bonds, a fundamental reaction in medicinal chemistry and material science.
• Chemical Biology & Proteomics Research: Used in the development of chemical probes and activity-based protein profiling (ABPP) agents to study enzyme function.
• Advanced Material Synthesis: Employed in the creation of organic electronic materials, polymers, and liquid crystals where precise molecular architecture is required.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with novel modes of action.
• Academic & Industrial R&D: A valuable tool for synthetic chemists exploring new reaction methodologies and complex molecule construction.

Basic Information

Product Name	Benzoic Acid, 2-Amino-4-Borono-, 1-Ethyl Ester (9Ci)
CAS No.	573675-99-7
Molecular Formula	C9H12BNO4
Molecular Weight	209.01 g/mol
Synonyms	2-Amino-4-(ethoxyboryl)benzoic acid; 1-Ethyl 2-amino-4-boronobenzoate; 4-Borono-2-aminobenzoic acid ethyl ester; Ethyl 2-amino-4-boronobenzoate; (2-Amino-4-(ethoxyboryl)phenyl)formic acid; B-[2-(Ethoxycarbonyl)-5-aminophenyl]boronic acid; Benzoic acid, 2-amino-4-borono-, ethyl ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-Amino-4-Borono-, 1-Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for sensitive applications like Suzuki coupling. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.